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More than a month after House Republicans surprised Washington by聽聽for Trump's tax breaks and spending cuts package, Senate Republicans voted Thursday to start working on聽. The聽52-48, largely party-line vote set the stage for back-to-back Senate all-nighters spilling into Friday and the weekend.

Work on the multitrillion-dollar package comes as聽聽in the aftermath Trump's聽, complicating an already difficult political and procedural undertaking.

聽R-S.D., opened the chamber Thursday saying they were expected to begin 鈥渁s soon as today鈥� embarking on what they hope will become the GOP鈥檚 signature domestic policy package.

Trump says he's on board and Republicans, in control of Congress, are eager to show the party is making progress toward delivering on their campaign promises. Still, it's long weeks, if not months, to go toward a final product.

顿别尘辞肠谤补迟蝉,听, don't have the votes to stop the GOP plan but they intend to use the procedural tools available to prolong the process. Democrats argue that Republicans are focusing on tax breaks for the wealthy at the expense of the programs and services millions of Americans rely on for help with health care, child care, school lunches and other everyday needs.

鈥淭hey鈥檙e mean, they鈥檙e nasty, they鈥檙e uncaring,"聽聽of New York said of the Republicans.

Senate Democrats started consuming up to 25 hours of their available debate time, holding the floor into the night and railing against potential GOP cuts to Medicaid, veterans programs, DOGE cuts and the impact of Trump's tariffs.

Sen. Jeff Merkley of Oregon, the ranking Democrat on the Budget committee, repeated a slogan he has shared: 鈥淔amilies lose and billionaires win.鈥�

鈥淭hat," he said, 鈥渋s the Republican plan.鈥�

Fundamental to the Senate package is making sure Trump鈥檚 first-term tax cuts, which are set to expire at the end of the year, are continued and made a permanent fixture of the tax code. The senators also will consider adding Trump's proposed tax cuts on tipped wages, Social Security income and others.

The Senate package also would bolster border security funds by about $175 billion to carry out聽, which is running short of cash, and it would add national security funds for the Pentagon 鈥� all priorities the Senate GOP tucked into an earlier version that was panned by House Republicans.

What's unclear is how it will all be paid for, since Republican deficit hawks typically require spending offsets to help defray the lost tax revenue and avoid piling onto the nation's $36 trillion debt load.

While House Republicans approved their package with $4.5 trillion in tax breaks and up to $2 trillion in spending cuts, the聽.

Senate Budget Committee Chairman Lindsey Graham, R-S.C., is making the case that since the existing Trump tax breaks聽, they are not considered new and do not need to be offset with reductions in spending 鈥� an approach Democrats compare to 鈥済oing nuclear鈥� with the normal rules. Democrats vowed to put the strategy to the test before the Senate parliamentarian.

Instead, Senate Republicans are considering offsets mostly for any new Trump tax breaks. Raising alarms from the most conservative budget hawks, the senators set a floor of about $4 billion in budget reductions to health and other programs 鈥� a fraction of the package's expected $4 trillion-plus price tag for tax breaks.

GOP leaders assure the deficit hawks in their own ranks that the legislation says the cuts can rise to as much as $2 trillion.

After an expected Friday night vote-a-rama, with dozens of amendments being offered to the package, the senators plan to stay into Saturday if needed to take a final vote to approve it, sending it to the House for action.

The House and Senate will ultimately need to merge their frameworks into a final product, expected in May, but House Speaker Mike Johnson's intention to have it all wrapped up by Memorial Day could prove optimistic.

The political environment is uncertain, and the public's appetite for steep budget cuts is being tested in real time, with Trump's聽聽headed by聽聽blazing through federal offices, firing thousands of workers and shuttering long-running government mainstays 鈥� from scientific research projects on diseases to educational services for schoolchildren to offices that help with Social Security, tax filing and the weather.

At the same time, the staunchest fiscal conservatives in both the House and Senate, many aligned with the Freedom Caucus, push for even more cuts.

Trump told senators publicly and privately this week he would have their backs, particularly when it comes to standing up for the spending reductions. At a White House announcing the tariffs Wednesday, Trump said the Senate plan had his 鈥渃omplete and total support.鈥�

The president's steep tariffs threw the global economy into a tailspin Thursday.

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Associated Press writers Leah Askarinam and Kevin Freking contributed to this report.